Description Von Hipple-lindau is an inherited multi-system disorder character by abnormal growth of blood vessels. The blood vessels normally grow like trees. In people with VHL, little knots of blood capilaries sometimes occur. These knots are called angiomas or hemogioblastomas. Growths may develop in the retina, certain areas of the brain, the spinal chord, adrenal glands, and other parts of the body.
- The inheretance pattern is an autosomal dominant pattern, witch means that one copy of the altered gene in each cell is sufficient to increase the risk of developing tumors and cysts.
Image 1
This is a microscopic microscope looking
at the cell of VHL.
Symptoms
VHL has over 300 symptoms just a few of them. Constant headaches, bad balance, limb weakness, walking problems, bad vision, and high blood pressure.
Prognosis-
The patients with VHL only live to be 40 or 50 years old. But to reduce the effects of VHL the patients have to under go intense treatments of radio-surgery.
Frequency- The frequency of a person getting VHL is 1 in 36,000 live births.
Questions-
1. What is the life expectancy of people with VHL?
2. What is the inheritance pattern of VHL? 3.What is the frequancy of people being born with VHL?
Von Hipple- Lindau
Description Von Hipple-lindau is an inherited multi-system disorder character by abnormal growth of blood vessels. The blood vessels normally grow like trees. In people with VHL, little knots of blood capilaries sometimes occur. These knots are called angiomas or hemogioblastomas. Growths may develop in the retina, certain areas of the brain, the spinal chord, adrenal glands, and other parts of the body.
- The inheretance pattern is an autosomal dominant pattern, witch means that one copy of the altered gene in each cell is sufficient to increase the risk of developing tumors and cysts.
Image 1
This is a microscopic microscope looking
at the cell of VHL.
Symptoms
VHL has over 300 symptoms just a few of them. Constant headaches, bad balance, limb weakness, walking problems, bad vision, and high blood pressure.
Prognosis-
The patients with VHL only live to be 40 or 50 years old. But to reduce the effects of VHL the patients have to under go intense treatments of radio-surgery.
Frequency- The frequency of a person getting VHL is 1 in 36,000 live births.
X-ray image of VHL
VHL really does bite!!!
Work cited
1. Michale Stalwitz.http://brighamandwomens.org. July 7 2006. http://shsgdp.wikspaces.com. April 14 2010.
2. http://medicalprognosis.com. November 24 2008. http://shsgdp.wikispaces.com. April 15 2010.
3.http://www.ncbi.nlm.nih.gov. September 2000. http://shsgdp.wikispaces.com.April 17 2010.
Questions-
1. What is the life expectancy of people with VHL?
2. What is the inheritance pattern of VHL?
3.What is the frequancy of people being born with VHL?